| Ex (nm) | 385 | Em (nm) | 499 |
| 分子量 | 230.14 | 溶剂 | DMSO |
| 存储条件 | 在零下15度以下保存, 避免光照 |
产品基本信息
产品名称：7-羟基-4-三氟甲基香豆素
CAS：575-03-1
储存条件：-15℃避光防潮
保质期：36个月
产品物理化学光谱特性
分子量：230.14
溶剂：DMSO
激发波长(nm)：385
发射波长(nm)：502
产品介绍
7-羟基-4-三氟甲基香豆素是美国AAT Bioquest生产的香豆素类染料，这种复合物被用作以7-羟基-4-三氟甲基香豆素为基础的酶底物校准标准液，它是pH依赖性荧光。百萤生物是AAT Bioquest的中国代理商，为您提供优质的7-羟基-4-三氟甲基香豆素。
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溶解方案(溶剂以说明书为准)
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 434.518 µL | 2.173 mL | 4.345 mL | 21.726 mL | 43.452 mL |
| 5 mM | 86.904 µL | 434.518 µL | 869.036 µL | 4.345 mL | 8.69 mL |
| 10 mM | 43.452 µL | 217.259 µL | 434.518 µL | 2.173 mL | 4.345 mL |
参考文献
Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes
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Journal: Methods Mol Biol (2006): 97
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil)
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Journal: Drug metab Dispos (2004): 267
Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver
Authors: Dean B, Arison B, Chang S, Thomas PE, King C.
Journal: Arch Biochem Biophys (2004): 55
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases
Authors: Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.
Journal: Drug metab Dispos (2004): 587
Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10
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Journal: Drug metab Dispos (2003): 528
Generation and validation of rapid computational filters for cyp2d6 and cyp3a4
Authors: Ekins S, Berbaum J, Harrison RK.
Journal: Drug metab Dispos (2003): 1077
Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity
Authors: Huynh HT, Teel RW.
Journal: Anticancer Res (2002): 1699
evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes
Authors: Renwick AB, Lavignette G, Worboy PD, Williams B, Surry D, Lewis DF, Price RJ, Lake BG, Evans DC.
Journal: Xenobiotica (2001): 861
metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4
Authors: Renwick AB, Lewis DF, Fulford S, Surry D, Williams B, Worboys PD, Cai X, Wang RW, Price RJ, Lake BG, Evans DC.
Journal: Xenobiotica (2001): 187
CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes
Authors: Price RJ, Surry D, Renwick AB, Meneses-Lorente G, Lake BG, Evans DC.
Journal: Xenobiotica (2000): 781
